GANX
Gain Therapeutics, Inc.3.8600
-0.0900-2.28%
Dec 16, 4:00:01 PM EST
Earnings Call Transcripts
This Quarter (Q1 '26)
No earnings call transcript available yet
Last Quarter (Q4 '25)
No earnings call transcript available
Key Stats
Market Cap
148.46MP/E (TTM)
-Basic EPS (TTM)
-0.61Dividend Yield
0%Recent Filings
8-K
Phase 1b data stable
Gain Therapeutics reported 2025 net loss of $20.2M, down slightly from $20.4M in 2024, with R&D expenses dropping to $10.2M and cash rising to $20.8M. Phase 1b data for Parkinson's candidate GT-02287 showed stable MDS-UPDRS scores over 150 days and 81% GluSph reduction in high-baseline patients. Extension completes September 2026. Phase 2 starts 3Q26.
10-K
FY2025 results
Gain Therapeutics posted FY2025 net loss of $20.2M on $18.7M operating expenses, down from $20.4M loss on $20.4M expenses in FY2024, as R&D held steady at $10.2M amid Phase 1b Parkinson's enrollment completion while G&A fell 11% on lower stock comp. Cash burn eased to $18.5M from $18.9M, bolstered by $28.4M raised via ATM and offerings, ending with $20.8M runway into Q1 2027. Q4 saw 19 patients finish GT-02287's 90-day Part 1, with 16 electing 9-month extension signaling momentum toward Phase 2 in H2 2026. No capex or dividends; liquidity tightens absent funding. Substantial doubt persists on going concern amid Nasdaq compliance risks.
8-K
Phase 1b data strengthens GT-02287
Gain Therapeutics unveiled Phase 1b data for GT-02287 at AD/PD 2026, showing stable MDS-UPDRS scores over 150 days, a 6.7-point gap favoring high baseline GluSph patients, and DDC reductions after 90 days. Of 19 Part 1 completers, 16 joined the nine-month extension; DMC greenlit continuation. New GCase modulators led by GT-04686 prep for IND studies. Data bolsters disease-modifying hopes, yet risks loom per 10-K.
8-K
GT-02287 Phase 1b success
Gain Therapeutics posted its February 2026 investor presentation under Item 7.01, highlighting GT-02287's Phase 1b success in Parkinson's patients. The allosteric GCase modulator slashed CSF GluSph by 81% in high-baseline cases, driving sharp MDS-UPDRS motor score gains. Phase 2 kicks off 3Q26. Cash stands at $8.8M.
8-K
Positive GT-02287 Phase 1b biomarker data
Gain Therapeutics announced Phase 1b results for GT-02287 in Parkinson's patients: all with elevated CSF GluSph saw large decreases toward healthy levels after 90 days. The drug stayed well-tolerated; 79% of completers joined the nine-month extension ending September 2026. Cash funds operations through year-end 2026. Trial risks remain.
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