PMVP
PMV Pharmaceuticals, Inc.1.1800
-0.0200-1.67%
Dec 16, 4:00:00 PM EST
Earnings Call Transcripts
This Quarter (Q1 '26)
No earnings call transcript available yet
Last Quarter (Q4 '25)
No earnings call transcript available
Key Stats
Market Cap
62.79MP/E (TTM)
-Basic EPS (TTM)
-1.59Dividend Yield
0%Recent Filings
10-K
8-K
8-K
Rezatapopt Phase 2 data shines
PMV Pharma unveiled Phase 2 PYNNACLE data for rezatapopt, posting 34% ORR across 103 patients and 46% in ovarian cancer, with median durations of 7.6 and 8.0 months. Cash stands at $129.3 million, funding to Q1 2027 alongside planned ovarian NDA filing. Data fuels pivotal momentum. Burn quickened to $21.1 million Q3 net loss on R&D ramp.
10-Q
Q3 FY2025 results
PMV Pharmaceuticals posted a Q3 operating loss of $22.5M, up 3% y/y from $21.9M, driven by $18.2M R&D (up 8% y/y on CRO costs for rezatapopt Phase 2 trial) while G&A fell to $4.3M. YTD operating loss widened to $67.0M (up 11% y/y), with net loss $59.7M after $5.1M interest income offset by $2.2M NJ tax benefit. Cash burn hit $56.4M on operations; $129.3M in cash and marketable securities funds into Q1 2027. Leases downsized post-2024 termination. Diluted EPS aligns at -$0.40 on 53M shares. Steady burn fuels rezatapopt momentum. Clinical trial delays loom large.
8-K
Rezatapopt Phase 2 data shines
PMV Pharma disclosed PYNNACLE Phase 2 interim data on September 10, 2025, showing rezatapopt's 33% ORR across 97 evaluable TP53 Y220C-mutated solid tumor patients, with 43% ORR and 7.6-month median duration in ovarian cancer. Heavily pretreated patients tolerated it well—mostly grade 1/2 TRAEs, 3.7% discontinuations. NDA planned for 1Q2027 in platinum-resistant/refractory ovarian cancer. Cash lasts through 1Q2027.
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